In terms of dosing, Semaglutide is available in a once-weekly injectable form, while tirzepatide is also a once-weekly injectable medication. However, Tirzepatide comes in higher doses than semaglutide, and it has been shown to be more effective at lowering blood sugar levels and promoting weight loss in clinical trials.
Overall, both Semaglutide and Tirzepatide are effective medications for the treatment of type 2 diabetes, but they work through different mechanisms and have different dosing requirements. The choice between the two medications may depend on the individual patient’s needs and preferences, as well as their response to the medication.
Compounding is the art and science of creating customized medications for patients per then prescription orders of licensed prescribing practitioners (Dr, NP. PA). The practice of compounding is highly regulated by the Florida State Board of Pharmacy as well as the FDA.
Congress passed the Food, Drug and Cosmetic Act which called for creation of the FDA. The act contains very rigorous standards for compounding pharmacies within the DQSA chapters of the act.
There are several patented brands and dosage forms of Semaglutide and Tirzepatide including injectables and oral tablets.
Despite the inability of the manufacturers to keep up with demand, they understandably resent compounding pharmacies and actively disseminate disinformation, implying compounders are not qualified to produce safe and effective products.
To date, there have been no reports of patient harm from compounded Semaglutide other than the most commonly listed side effects seen with the branded Semaglutide which would include nausea, vomiting, and slowed bowel transit times. When patients see negative media reporting concerning compounded Semaglutide, they would be well advised to consider the purpose behind the negative reporting- to create an emotional bias against compounding pharmacy and their products.
To establish trust and confidence in your choice of compounding pharmacy, we highly suggest patients:
- Visit their compounding pharmacy, take a tour of the facility noting cleanroom cleanliness, proper garbing/gowning and sterile techniques used.
- Ask for copies of the required testing of sterile products from independent analytical labs including proof of sterility and endotoxin tests on each production batch as well as potency of the active ingredient.
- Ask for copies of the last inspection from the Texas State Board of Pharmacy compliance officers.